
Mice With No Mother?
Biotechnologists keep pushing the borders of what is possible in procreationBiotechnologists keep pushing the borders of what is possible in procreation. Mice pups have now been born with no mother and two fathers. It was done, apparently, by transforming skin cells from male mice into pluripotent stem cells and thence into egg cells with XX chromosomes. From the Guardian story: Male skin cells were reprogrammed into a stem cell-like state to create so-called induced pluripotent stem (iPS) cells. The Y-chromosome of these cells was then deleted and replaced by an X chromosome “borrowed” from another cell to produce iPS cells with two identical X chromosomes. “The trick of this, the biggest trick, is the duplication of the X chromosome,” said Hayashi. “We really tried to establish a system to duplicate the X chromosome.” Read More ›