Mind Matters Natural and Artificial Intelligence News and Analysis

CategoryCell biology

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IDP Clinical Trials: Illustrate the stages of clinical trials for drugs targeting intrinsically disordered proteins, from preclinical testing to phase III trials.
Type
post
Erik J. Larson
Date
March 14, 2025
Categorized
Artificial Intelligence, Cell biology
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AI in Biology: So Is This the End of the Experiment? No.

But a continuing challenge is that many of the most biologically important proteins don’t adopt a single stable structure. Their functions depend on structural fluidity
Erik J. Larson
March 14, 2025
6
Artificial Intelligence, Cell biology
The core issue AI isn’t just missing data — AlphaFold’s entire approach is built on assumptions that don’t apply to disordered proteins. Read More ›
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AlphaFold Accuracy Visualization on a Tablet Cutting-Edge Biochemical Analysis
Type
post
Erik J. Larson
Date
March 12, 2025
Categorized
Artificial Intelligence, Cell biology, Machine Learning
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AI in Biology: What Difference Did the Rise of the Machines Make?

AI works very well for proteins that lock into a single configuration, as many do. But intrinsically disordered ones don’t play by those rules
Erik J. Larson
March 12, 2025
6
Artificial Intelligence, Cell biology, Machine Learning
The resulting problems aren’t a temporary bug — they’re a basic limitation of training a machine learning model on a dataset where proteins always fold neatly. Read More ›
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the elaborate process of protein folding, essential for proper function within living organisms
Type
post
Erik J. Larson
Date
March 11, 2025
Categorized
Artificial Intelligence, Cell biology
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AI in Biology: AI Meets Intrinsically Disordered Proteins

Protein folding — the process by which a protein arrives at its functional shape — is one of the most complex unsolved problems in biology
Erik J. Larson
March 11, 2025
7
Artificial Intelligence, Cell biology
The mystery of protein folding remains unsolved because, as is so often the case with AI narratives, the reality is much more complicated than the hype. Read More ›