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TagAlphafold2

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IDP Clinical Trials: Illustrate the stages of clinical trials for drugs targeting intrinsically disordered proteins, from preclinical testing to phase III trials.

AI in Biology: So Is This the End of the Experiment? No.

But a continuing challenge is that many of the most biologically important proteins don’t adopt a single stable structure. Their functions depend on structural fluidity
The core issue AI isn’t just missing data — AlphaFold’s entire approach is built on assumptions that don’t apply to disordered proteins. Read More ›