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Light rays through the black window. Toned photo

Can LSD Help Us Understand the Mind–Brain Relationship?

Is the mind generated by the brain or does the brain merely focus the mind on the current scene? An experiment sheds some light

In a fascinating article inThe Guardian titled “Acid test: scientists show how LSD opens doors of perception,” science editor Ian Sample discusses recent research on the mechanism by which LSD alters the brain and the mind. He begins by quoting Aldous Huxley (1894–1963) who noted that LSD “lowers the efficiency of the brain as an instrument for focusing the mind on the problems of life.” Remarkably, recent work in neuroscience supports Huxley’s view. The research, conducted at Cornell University, confirms what has been called the Rebus model of psychedelics. Rebus is a rough acronym for “relaxed beliefs under psychedelics”; the model proposes that the brain is essentially a prediction engine for daily life. In this model, the brain processes information…

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Can a Pill Change Your Mind About Basic Issues in Life?

The legalization of mind-altering drugs raises the question in the research community

An Oxford researcher into psychedelics thinks so. Eddie Jacobs offers a disturbing premise, “What if a pill can change your politics or religious beliefs?” The background is that some jurisdictions are contemplating licencing the otherwise illegal psychedelic psilocybin (“magic mushrooms”) in the near future as a treatment for depression. He writes, How would you feel about a new therapy for your chronic pain, which—although far more effective than any available alternative—might also change your religious beliefs? Or a treatment for lymphoma that brings one in three patients into remission, but also made them more likely to vote for your least preferred political party? Eddie Jacobs, “What if a Pill Can Change Your Politics or Religious Beliefs?” at Scientific American (October…