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Foam cell, a macrophage cell with lipid droplets

Life Is So Wonderfully Finely Tuned That It’s Frightening

A mathematician who uses statistical methods to model the fine tuning of molecular machines and systems in cells reflects…

In Episode 2, “Life is fine-tuned in a fearful and wonderful way” (September 9, 2021), Swedish mathematician Ola Hössjer discusses fine tuning in biology with Walter Bradley Center director Robert J. Marks. It’s a bit scary to think that each of our cells is like a city because it certainly gives us some idea of all the things that can (but, thankfully, usually don’t) go wrong, Note: Episode 1 was “Run the gambit of complexity” (September 20, 2021) discussed here and here. https://episodes.castos.com/mindmatters/Mind-Matters-Episode-151-Hossjer-Diaz.mp3 This portion begins at 01:14 min. A partial transcript, Show Notes, and Additional Resources follow. Robert J. Marks: Today we’re going to talk about fine tuning in biology. How biology is fine tuned to allow us to…

Intestinal villi, mucosa intestinal. Bacteria and microbes in intestines. Microscopic villi and capillary. Human intestine, chronic disease. Hepatitis viruses, influenza, cell infections, 3D Rendering

Surprisingly, Many “Alien” Cells Live Inside Us

One zoologist thinks that they create our sense of self

At New Scientist, Graham Lawton asks us to think about them: For starters, we are chimeras: some parts of us are human, but genetically not “us”. Most, if not all, of us contain a few cells from our mother, our grandmothers and even elder siblings that infiltrated our bodies in the uterus. Women who have carried children host such cells too. “Something like 65 per cent of women, even in their 70s, when autopsies were performed, had cells in their brains that were not theirs,” says David Linden at Johns Hopkins University in Maryland. Chimeric cells have been found to contribute to both good and bad health, for example promoting wound healing but also triggering autoimmune disease. Graham Lawton, “Why…