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Woman scientist holding lab rat, medicine development, tests on animals

An Old Rat With No Brain Raises Some Very Interesting Questions

The researchers had no idea how strange their lab rat was until, in a routine procedure, they scanned its head

Yes, R222 was only a rat. A rat that turned out to have no brain. But here’s the thing: R222 had lived a normal life as a lab rat for two whole years. According to rat specialists, that’s like 70 human years. Researchers were, to say the least, puzzled. The story begins with a scientist scanning the brains of “very old” lab rats as part of a study on aging. Except that subject R222, otherwise a conventional rat, didn’t seem to have a brain. The brain cavity had collapsed and filled with fluid (hydrocephalus). We can see from the photo that where the control rat has brain, R222 has fluid: On further investigation, researchers found that all brain functions had…