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Do Larger Brains Make Us Human? Is That All?

Brain organoid studies suggest a “key genetic switch” that makes human brains grow larger than ape brains

In a study of “mini-brains” (brain organoids), the size of a pea, grown in a dish and incapable of further development, researchers have discovered a “key genetic switch” that makes human brains grow three times larger than primate brains: This new research, published in the journal Cell, used brain organoids to show that this transition occurs more slowly in humans compared to gorillas and chimpanzees – over seven days, compared to five. The progenitor cells in human brain organoids not only retained their cylindrical shape for longer, but also split more frequently so more cells were produced. This was linked to a gene called ZEB2, which switches on sooner in gorilla brain organoids than in human. By delaying the effects…