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TagNecrosignals

antibiotic-resistant-bacteria-inside-a-biofilm-3d-illustration-realistic-scientific-background-stockpack-adobe-stock.jpg
Antibiotic resistant bacteria inside a biofilm, 3D illustration. Realistic scientific background

Do Bacteria Warn Others While Dying from Antibiotics?

Scientists are learning more about the complex ways bacteria overcome efforts to control them

That’s what we learn from a new open-access paper in Nature titled “Dead cells release a ‘necrosignal’ that activates antibiotic survival pathways in bacterial swarms.” It’s sometimes described as “screams,” but it’s actually a release of chemicals, which amounts to the same thing: a warning to prepare for an onslaught of antibiotics. The scientists also noted another curious factor: The cascade of genes turned on by necrosignals not only protected the surviving swarm from antibiotics, but promoted future resistance to the compounds that killed their comrades. What’s more, the scientists realized that subpopulations of swarm bacteria were genetically variable; some were more susceptible to the antibiotics than others. Swarms of bacteria may collectively cultivate different subpopulations as an evolutionary survival…