Current treatments for dementia are not very effective; capturing the mysterious moments of paradoxical lucidity may point to new and better ones.
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Even since neuroscientists started imaging the brain, they’ve been turning up cases where people are missing brain parts we would expect them to need in order to do something — but they are doing that very thing anyway. One example, written up in LiveScience in 2019, concerns women who are missing their olfactory bulbs (illustrated) but can still smell: Researchers have discovered a small group of people that seem to defy medical science: They can smell despite lacking “olfactory bulbs,” the region in the front of the brain that processes information about smells from the nose. It’s not clear how they are able to do this, but the findings suggest that the human brain may have a greater ability to Read More ›
So much compassion! A disabled woman with quadriplegia named Rose Finlay in Canada has asked to be euthanized because she is destitute, and the disability benefits she applied for would not arrive in time for her to be properly housed and cared for. From the CBC story: A quadriplegic woman in Bowmanville, Ont., has applied for medical assistance in dying (MAID), saying it’s easier to access than the support services she needs to live her life comfortably. Receiving assistance takes a long time. But to be made dead? Not so much: The single mother of three boys previously supported her family with earnings from disability advocacy work through her company, Inclusive Solutions. That’s also how she could afford to hire her own support Read More ›
Alas. The president of Portugal just signed into law a bill legalizing euthanasia by lethal injection. It is not limited to the terminally ill — which is at least honest, since that is not what euthanasia/assisted suicide is really all about. From the Reuters story: The law specifies that people would be allowed to request assistance in dying in cases when they are “in a situation of intense suffering, with definitive injury of extreme gravity or serious and incurable disease.” It establishes a two-month gap between accepting a request and the actual procedure and makes psychological support mandatory. Strict guidelines and all that jazz. Not only are they unlikely to be strictly enforced but will soon be redefined from protections to barriers, Read More ›
For today’s featured video from COSM 2022, watch Babak Parviz, Vice President at Amazon, lead a discussion on synthetic biology, the multi-disciplinary field that applies engineering principles to redesign biological systems for new purposes. The panel focuses on bio-medical technologies that hold great promise for curing diseases and even counteracting human aging. For more material on the topic, see this piece on Altos Labs and their work on bio-longevity. Part of their project also involves artificial intelligence research: Altos Labs’ vision isn’t too far removed from that of the transhumanists who want to computerize human consciousness. For them, however, longevity is a junior varsity goal — what we really need is a way to live forever. Harrison quips at the Read More ›
Whether to treat mental health issues with psychotherapy or drugs has sometimes led to pitting one against the other. For example, as Cambridge neuroscientist Camilla Nord has noted, in a report that no longer seems to be online, the British Psychological Society’s Division of Clinical Psychology stated in 2016 that “There is no firm evidence that mental distress is primarily caused by biochemical imbalances, genes, or something going wrong in the brain …” Rather, the Society cited childhood trauma, abuse, and poverty as causes, to be remedied by political and social change. Other studies (here is a systematic review) found the same thing. Nord responds that mental disorders are brain disorders. However, she does not resort to simplistic claims that Read More ›
In the podcast released last Thursday, Walter Bradley Center director Robert J. Marks interviewed pediatric neurologist Dr. Andrew Knox from the University of Wisconsin School of Medicine and Public Health on “Ways the brain can break” (#220, January 5, 2023). What follows is Part 4 of the discussion, “When it’s not clear if a disorder is from the brain or the mind…” Here are Part 1: How our brains are — and aren’t — like computers, Part 2: What is happening when children have strokes or dementia signs?, and Part 3: How do strokes, dementia offer insight into how the brain works? https://mindmatters.ai/wp-content/uploads/sites/2/2022/12/Mind-Matters-220-Andrew-Knox-Episode-1.mp3 This portion begins at roughly 25:15 min. A partial transcript and notes, and Additional Resources follow. Epileptic Read More ›
In the podcast released last Thursday, Walter Bradley Center director Robert J. Marks interviewed pediatric neurologist Dr. Andrew Knox from the University of Wisconsin School of Medicine and Public Health on “Ways the brain can break” (#220, January 5, 2023). What follows is from Part 3 of the discussion. Here’s Part 1: How our brains are — and aren’t — like computers and Part 2: What is happening when children have strokes or dementia signs? https://mindmatters.ai/wp-content/uploads/sites/2/2022/12/Mind-Matters-220-Andrew-Knox-Episode-1.mp3 This portion begins at roughly 18:25 min. A partial transcript and notes, and Additional Resources follow. The discussion began with the question, “How does the brain store memories?” Andrew Knox: There are different schemes for storing memories, but patients with Alzheimer’s seem to have Read More ›
In the podcast released yesterday, Walter Bradley Center director Robert J. Marks interviewed pediatric neurologist Dr. Andrew Knox from the University of Wisconsin School of Medicine and Public Health on “Ways the brain can break” (#220, January 5, 2023). What follows reflects Part 2 of the discussion. Here’s Part 1: How our brains are — and aren’t — like computers. https://mindmatters.ai/wp-content/uploads/sites/2/2022/12/Mind-Matters-220-Andrew-Knox-Episode-1.mp3 This portion begins at roughly 10:50 min. A partial transcript and notes, and Additional Resources follow. Andrew Knox: If you had a stroke in what we would call a primary motor area, an area with the connections to motor pathways through the rest of the body — all of those patients might lose the ability to move their arm Read More ›
In the podcast released today, Walter Bradley Center director Robert J. Marks interviewed pediatric neurologist Dr. Andrew Knox from the University of Wisconsin School of Medicine and Public Health on “Ways the brain can break” (#220, January 5, 2023): The brain is a marvelous organ still not understood. Artificial neural networks are supposed to be a simulation of the human brain. But comparing the brain to an artificial neural network is like comparing the human heart to a pump handle. Dr. Andrew Knox and Dr. Robert J. Marks discuss the brain, aging, and neurology. https://mindmatters.ai/wp-content/uploads/sites/2/2022/12/Mind-Matters-220-Andrew-Knox-Episode-1.mp3 This portion begins at 00:04 min. A partial transcript and Additional Resources follow. Robert J. Marks: I got to ask you kind of a personal Read More ›
PhD student Cecily Whiteley and philosophy prof Jonathan Birch, both of the London School of Economics and Political Science, think that depression is often misunderstood. In this 2021 article, noted again at Psyche, they point out that it is not just “feeling low”; it is an altered form of consciousness: The psychologist Andrew Solomon hints at some of these transformations in his memoir The Noonday Demon (2001): “When you are depressed, the past and future are absorbed entirely by the present moment, as in the world of a three-year-old. You cannot remember a time when you felt better, at least not clearly; and you certainly cannot imagine a future time when you will feel better. Being upset, even profoundly upset, Read More ›
Around this time of year, the factories that produce Apple’s iPhones hire thousands of additional workers to meet the demand for the holiday season. While Apple is an American company and the electronics are designed in-house, the manufacturing is done overseas where labor costs are cheaper. One of the largest manufacturers for Apple’s iPhone products is Hon Hai Technology Group, better known as Foxconn, a Taiwan-based company with factories in several countries, including mainland China. One of its largest facilities is in Zhengzhou, the capital of Henan province — dubbed “iPhone City” by the locals. Thus the Zhengzhou Foxconn factory was slated to make 80% of the iPhone 14 models and 85% of the iPhone Pro models before the end Read More ›
A US Senate interim report has recently concluded that that “the Covid-19 pandemic was, more likely than not, the result of a research-related incident.” The 35-page report, prepared by the minority oversight staff of the of the Senate Committee on Health, Education, Labor, and Pensions (HELP), used publicly available documentation to justify the findings. However, it did not include the 236-page report submitted by language expert Toy Reid, who analyzed Chinese Communist Party dispatches between scientists at the Wuhan Institute of Virology (WIV) and their supervisors in Beijing. Katherine Eban of Vanity Fair and Jeff Kao of ProPublica were given advanced access to the Senate researchers’ documents and spent months conducting their own investigation. They interviewed Reid, talked with members Read More ›
Earlier this week, we looked at the recent news that Facebook has a special portal for government to look in and report “disinformation,” — as if government, in a highly charged political atmosphere, were some kind of neutral third party. The assignment of some sort of neutrality to power sources or experts who may not be neutral or have any reason to be is one of the characteristics of fact-checking, as it has developed over the last decade in mainstream and social media. Why was the Wuhan lab leak theory supposed to be a conspiracy? In that context, let’s look at the claim that COVID-19 originated in an accident at a high-level virus lab in the upcountry Chinese city of Read More ›
Some children have half of their brains removed (hemispherectomy) to control massive seizures that would otherwise destroy the child’s whole brain. Specialists were surprised that the children functioned fairly normally — certainly compared to what would have been expected. A recent study of post-hemispherectomy patients has provided dramatic evidence of rewiring: An unprecedented study of brain plasticity and visual perception found that people who, as children, had undergone surgery removing half of their brain correctly recognized differences between pairs of words or faces more than 80% of the time. Considering the volume of removed brain tissue, the surprising accuracy highlights the brain’s capacity — and its limitations — to rewire itself and adapt to dramatic surgery or traumatic injury. The Read More ›
We don’t often hear about researchers crying but when researchers at Ovid Therapeutics heard the test results for their drug, gaboxadol, they couldn’t help it. They were testing the sleep-inducing drug to help with the symptoms of Angelman Syndrome, a rare neurogenetic disorder that appears in infancy. It results in a variety of developmental problems such as walking and balance disorders, inability to speak or sleep properly, gastrointestinal issues, and seizures. It affects people in different ways and to different degrees. Notably, those who cope with Angelman smile and laugh a lot and have a normal lifespan. The OVID team had high hopes for gaboxadol in August of this year because even improving the quality of sleep would help sufferers Read More ›
Earlier this month, we looked at claims that robots are going to scarf up everyone’s jobs. That was a bonus feature in the Science Uprising series. In another bonus interview, “John Lennox on the Transhumanist Claim AI Will Turn Humans into Gods” (October 17, 2022), Oxford mathematician Lennox talks about claims that 1) computers are taking over and that 2) we will merge with them (transhumanism). Lennox is the author of 2084: Artificial Intelligence and the Future of Humanity (2020). This is the first of two parts, where he talks mainly about narrow AI but then gets into the topic of artificial general intelligence (AGI). A partial transcript and notes follow: John Lennox: The typical AI system consists of a Read More ›
In the United States alone, about 795,000 people suffer strokes each year, leading to varying degrees of paralysis. Post-stroke rehabilitation has come a long way in recent decades and one area of focus is robotic-assisted rehabilitation for both the upper and the lower body. That’s partly a medical issue and an economic one. As Physiopedia explains, It is used to supplement or facilitate rehabilitation by assisting in the repetitive labor-intensive manual therapy that is normally administered by therapists. This decreases the time demands on therapists as the robotic devices can help move the patient’s limbs during exercises, thereby increasing the amount of therapy for each patient and increasing the number of patients undergoing therapy simultaneously.” Here’s a demonstration of a Read More ›
We are always learning new, mostly hopeful, things about the human brain. This one may help medics treat depression: Scientists believe that the structure of the adult brain is generally rigid and incapable of rapid changes; now new work has shown that this is not true. German researchers have shown that in-patient treatment for depression can lead to an increase in brain connectivity, and those patients who respond well to this treatment show a greater increase in connectivity than those who don’t. European College of Neuropsychopharmacology, “Scientists discover structure of adult brain — previously thought to be fixed — is changed by treatment” at Eurekalert (October 17, 2022) The paper will be presented at the 35th European College of Neuropsychopharmacology Read More ›
Columbia University neurologist Jan Claassen and Harvard medical school neurologist Brian L. Edlow introduce us to a vital new concept in consciousness: “covert consciousness,” which is experienced by 15–20% of people who are in a coma: Thirty-year-old New York City resident Maria Murkevich, for example, suffered a ruptured blood vessel in her brain and was comatose. Conventional tests (wiggle your toes, etc.) produced no response but her loved ones still believed she was “in there.”: They were right. But it took a high-tech method to demonstrate that: The medical team gave her an EEG — placing sensors on her head to monitor her brain’s electrical activity — while they asked her to “keep opening and closing your right hand.” Then Read More ›